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Hepatotoxicity Induced by Sophora flavescens and Hepatic Accumulation of Kurarinone, a Major Hepatotoxic Constituent of Sophora flavescens in Rats

Our previous study showed that kurarinone was the main hepatotoxic ingredient of Sophora flavescens, accumulating in the liver. This study characterized the mechanism of Sophora flavescens extract (ESF) hepatotoxicity and hepatic accumulation of kurarinone. ESF impaired hepatic function and caused f...

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Detalles Bibliográficos
Autores principales: Jiang, Peng, Zhang, Xiuwen, Huang, Yutong, Cheng, Nengneng, Ma, Yueming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150336/
https://www.ncbi.nlm.nih.gov/pubmed/29068394
http://dx.doi.org/10.3390/molecules22111809