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Hepatotoxicity Induced by Sophora flavescens and Hepatic Accumulation of Kurarinone, a Major Hepatotoxic Constituent of Sophora flavescens in Rats
Our previous study showed that kurarinone was the main hepatotoxic ingredient of Sophora flavescens, accumulating in the liver. This study characterized the mechanism of Sophora flavescens extract (ESF) hepatotoxicity and hepatic accumulation of kurarinone. ESF impaired hepatic function and caused f...
Autores principales: | Jiang, Peng, Zhang, Xiuwen, Huang, Yutong, Cheng, Nengneng, Ma, Yueming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150336/ https://www.ncbi.nlm.nih.gov/pubmed/29068394 http://dx.doi.org/10.3390/molecules22111809 |
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