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Disrupting VEGF–VEGFR1 Interaction: De Novo Designed Linear Helical Peptides to Mimic the VEGF(13-25) Fragment

The interaction between vascular endothelial growth factor (VEGF) and its receptors (VEGFR) has important implications in angiogenesis and cancer, which moved us to search for peptide derivatives able to block this protein–protein interaction. In a previous work we had described a collection of line...

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Detalles Bibliográficos
Autores principales: Balsera, Beatriz, Bonache, M. Ángeles, Reille-Seroussi, Marie, Gagey-Eilstein, Nathalie, Vidal, Michel, González-Muñiz, Rosario, Pérez de Vega, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150346/
https://www.ncbi.nlm.nih.gov/pubmed/29143774
http://dx.doi.org/10.3390/molecules22111846