A Search for Dual Action HIV-1 Reverse Transcriptase, Bacterial RNA Polymerase Inhibitors

Using molecular modeling approach, potential antibacterial agents with triazole core were proposed. A moderate to weak level of antibacterial activity in most of the compounds have been observed, with best minimal inhibitory concentration (MIC) value of 0.003 mg/mL, as shown by the 15 against S. epi...

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Detalles Bibliográficos
Autores principales: Paneth, Agata, Frączek, Tomasz, Grzegorczyk, Agnieszka, Janowska, Dominika, Malm, Anna, Paneth, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150362/
https://www.ncbi.nlm.nih.gov/pubmed/29068373
http://dx.doi.org/10.3390/molecules22111808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150362/
https://www.ncbi.nlm.nih.gov/pubmed/29068373
http://dx.doi.org/10.3390/molecules22111808

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