Design, Synthesis, and Biological Evaluation of N,N-Disubstituted-4-arylthiazole-2-methylamine Derivatives as Cholesteryl Ester Transfer Inhibitors

Cholesteryl ester transfer protein (CETP) has been identified as a potential target for cardiovascular disease (CVD) for its important role in the reverse cholesteryl transfer (RCT) process. In our previous work, compound 5 was discovered as a moderate CETP inhibitor. The replacement of the amide li...

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Detalles Bibliográficos
Autores principales: Wang, Xinran, Lin, Xuehua, Xu, Xuanqi, Li, Wei, Hao, Lijuan, Liu, Chunchi, Zhao, Dongmei, Cheng, Maosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150381/
https://www.ncbi.nlm.nih.gov/pubmed/29112169
http://dx.doi.org/10.3390/molecules22111925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150381/
https://www.ncbi.nlm.nih.gov/pubmed/29112169
http://dx.doi.org/10.3390/molecules22111925

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