Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells

Liver cancer is a progressive, irreversible and aggressive malignant disease, which has no effective chemotherapeutic drugs. RA-XII, a natural cyclopeptide isolated from the traditional Chinese medicine Rubia yunnanensis, exerts anti-cancer and anti-inflammatory activities. This work aimed to invest...

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Detalles Bibliográficos
Autores principales: Song, Lihua, Wang, Zhe, Wang, Yurong, Guo, Di, Yang, Jianhong, Chen, Lijuan, Tan, Ninghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150396/
https://www.ncbi.nlm.nih.gov/pubmed/29137114
http://dx.doi.org/10.3390/molecules22111934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150396/
https://www.ncbi.nlm.nih.gov/pubmed/29137114
http://dx.doi.org/10.3390/molecules22111934

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