Preparation and Bioactivity Assessment of Chitosan-1-Acetic Acid-5-Flurouracil Conjugates as Cancer Prodrugs

5-fluorouracil (5-FU) is a specific anti-cancer agent that is generally used to treat gastrointestinal, colorectal, and breast cancer. In this work, chitosan (CS) was extracted from local fish scales using an established method. 5-FU was then converted to 1-acetic acid-5-fluorouracil (FUAC) and reac...

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Detalles Bibliográficos
Autores principales: Mohammed, Mohsin O., Hussain, Kameran S., Haj, Nadia Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150397/
https://www.ncbi.nlm.nih.gov/pubmed/29117097
http://dx.doi.org/10.3390/molecules22111629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150397/
https://www.ncbi.nlm.nih.gov/pubmed/29117097
http://dx.doi.org/10.3390/molecules22111629

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