Cargando…

Studies for Improving a Rat Model of Alzheimer’s Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory

During the past 15 years, several genetically altered mouse models of human Alzheimer’s disease (AD) have been developed. These costly models have greatly facilitated the evaluation of novel therapeutic approaches. Injecting synthetic β-amyloid (Aβ) 1-42 species into different parts of the brain of...

Descripción completa

Detalles Bibliográficos
Autores principales: Kasza, Ágnes, Penke, Botond, Frank, Zsuzsanna, Bozsó, Zsolt, Szegedi, Viktor, Hunya, Ákos, Németh, Klaudia, Kozma, Gábor, Fülöp, Lívia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150403/
https://www.ncbi.nlm.nih.gov/pubmed/29156571
http://dx.doi.org/10.3390/molecules22112007