Synthesis and In Vitro Antiproliferative Activity of 11-Substituted Neocryptolepines with a Branched ω-Aminoalkylamino Chain

Neocryptolepine, which is a kind of tetracyclic indoloquinoline alkaloid, exhibits the inhibition of topoisomerase II and shows antiproliferative activity. The present study describes the synthesis and antiproliferative evaluation of several neocryptolepine analogues carrying a branched, functionali...

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Detalles Bibliográficos
Autores principales: Shaban, Elkhabiry, Świtalska, Marta, Wang, Li, Wang, Ning, Xiu, Fan, Hayashi, Ikuya, Ngoc, Tran Anh, Nagae, Sachie, El-Ghlban, Samah, Shimoda, Shiho, El Gokha, Ahmed Abdel Aleem, El Sayed, Ibrahim El Tantawy, Wietrzyk, Joanna, Inokuchi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150407/
https://www.ncbi.nlm.nih.gov/pubmed/29137152
http://dx.doi.org/10.3390/molecules22111954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150407/
https://www.ncbi.nlm.nih.gov/pubmed/29137152
http://dx.doi.org/10.3390/molecules22111954

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