Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis

BACKGROUND: Type 2 diabetes (T2D) is a heterogeneous disease for which (1) disease-causing pathways are incompletely understood and (2) subclassification may improve patient management. Unlike other biomarkers, germline genetic markers do not change with disease progression or treatment. In this pap...

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Detalles Bibliográficos
Autores principales: Udler, Miriam S., Kim, Jaegil, von Grotthuss, Marcin, Bonàs-Guarch, Sílvia, Cole, Joanne B., Chiou, Joshua, Boehnke, Michael, Laakso, Markku, Atzmon, Gil, Glaser, Benjamin, Mercader, Josep M., Gaulton, Kyle, Flannick, Jason, Getz, Gad, Florez, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150463/
https://www.ncbi.nlm.nih.gov/pubmed/30240442
http://dx.doi.org/10.1371/journal.pmed.1002654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150463/
https://www.ncbi.nlm.nih.gov/pubmed/30240442
http://dx.doi.org/10.1371/journal.pmed.1002654

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