Environmental Enrichment and Social Isolation Mediate Neuroplasticity of Medium Spiny Neurons through the GSK3 Pathway

Resilience and vulnerability to neuropsychiatric disorders are linked to molecular changes underlying excitability that are still poorly understood. Here, we identify glycogen-synthase kinase 3β (GSK3β) and voltage-gated Na(+) channel Nav1.6 as regulators of neuroplasticity induced by environmentall...

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Detalles Bibliográficos
Autores principales: Scala, Federico, Nenov, Miroslav N., Crofton, Elizabeth J., Singh, Aditya K., Folorunso, Oluwarotimi, Zhang, Yafang, Chesson, Brent C., Wildburger, Norelle C., James, Thomas F., Alshammari, Musaad A., Alshammari, Tahani K., Elfrink, Hannah, Grassi, Claudio, Kasper, James M., Smith, Ashley E., Hommel, Jonathan D., Lichti, Cheryl F., Rudra, Jai S., D’Ascenzo, Marcello, Green, Thomas A., Laezza, Fernanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150488/
https://www.ncbi.nlm.nih.gov/pubmed/29642012
http://dx.doi.org/10.1016/j.celrep.2018.03.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150488/
https://www.ncbi.nlm.nih.gov/pubmed/29642012
http://dx.doi.org/10.1016/j.celrep.2018.03.062

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