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Tuning the Flexibility of Glycine-Serine Linkers To Allow Rational Design of Multidomain Proteins
[Image: see text] Flexible polypeptide linkers composed of glycine and serine are important components of engineered multidomain proteins. We have previously shown that the conformational properties of Gly-Gly-Ser repeat linkers can be quantitatively understood by comparing experimentally determined...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150656/ https://www.ncbi.nlm.nih.gov/pubmed/29168376 http://dx.doi.org/10.1021/acs.biochem.7b00902 |