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Tuning the Flexibility of Glycine-Serine Linkers To Allow Rational Design of Multidomain Proteins

[Image: see text] Flexible polypeptide linkers composed of glycine and serine are important components of engineered multidomain proteins. We have previously shown that the conformational properties of Gly-Gly-Ser repeat linkers can be quantitatively understood by comparing experimentally determined...

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Detalles Bibliográficos
Autores principales:	van Rosmalen, Martijn, Krom, Mike, Merkx, Maarten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150656/ https://www.ncbi.nlm.nih.gov/pubmed/29168376 http://dx.doi.org/10.1021/acs.biochem.7b00902

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