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Re-expression of the p53 Gene by Inhibiting the Mdm-2 Receptor in Wild-type p53 Tumors for the Treatment of Glioblastoma: A Mini Review

Glioblastoma multiforme (GBM) has been the topic of immense research in recent years. The suitable therapeutic approach towards this wild-type p53 tumor has been the topic of ongoing discussion for some decades now. There has been a substantial debate about the role of mouse double minute-2 (MDM-2)...

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Detalles Bibliográficos
Autores principales: Ahmed, Syed Ijlal, Bareeqa, Syeda Beenish, Samar, Syeda Sana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150754/
https://www.ncbi.nlm.nih.gov/pubmed/30254823
http://dx.doi.org/10.7759/cureus.3034