Cargando…
Direct α-alkylation of primary aliphatic amines enabled by CO(2) and electrostatics
Primary aliphatic amines are important building blocks in organic synthesis due to the presence of a synthetically versatile NH(2) group. While N-functionalization of primary amines is well-established, selective C-functionalization of unprotected primary amines remains challenging. Here we report t...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150826/ https://www.ncbi.nlm.nih.gov/pubmed/30061617 http://dx.doi.org/10.1038/s41557-018-0085-9 |