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Safety and immunogenicity of an attenuated Chinese pseudorabies variant by dual deletion of TK&gE genes

BACKGROUND: Since the outbreak of a new emerging virulent pseudorabies virus mutant in Chinese pig herds, intensive research has been focused on the construction of novel gene deletion vaccine based on the variant virulent viruses. An ideal vaccine candidate is expected to have a balanced safety and...

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Detalles Bibliográficos
Autores principales: Wang, Jichun, Song, Zengcai, Ge, Aimin, Guo, Rongli, Qiao, Yongfeng, Xu, Mengwei, Wang, Zhisheng, Liu, Yamei, Zheng, Yating, Fan, Hongjie, Hou, Jibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150974/
https://www.ncbi.nlm.nih.gov/pubmed/30241529
http://dx.doi.org/10.1186/s12917-018-1536-7