Cargando…
Safety and immunogenicity of an attenuated Chinese pseudorabies variant by dual deletion of TK&gE genes
BACKGROUND: Since the outbreak of a new emerging virulent pseudorabies virus mutant in Chinese pig herds, intensive research has been focused on the construction of novel gene deletion vaccine based on the variant virulent viruses. An ideal vaccine candidate is expected to have a balanced safety and...
Autores principales: | Wang, Jichun, Song, Zengcai, Ge, Aimin, Guo, Rongli, Qiao, Yongfeng, Xu, Mengwei, Wang, Zhisheng, Liu, Yamei, Zheng, Yating, Fan, Hongjie, Hou, Jibo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150974/ https://www.ncbi.nlm.nih.gov/pubmed/30241529 http://dx.doi.org/10.1186/s12917-018-1536-7 |
Ejemplares similares
-
An inactivated gE-deleted pseudorabies vaccine provides complete clinical protection and reduces virus shedding against challenge by a Chinese pseudorabies variant
por: Wang, Jichun, et al.
Publicado: (2016) -
Construction of pseudorabies virus variant attenuated vaccine: codon deoptimization of US3 and UL56 genes based on PRV gE/TK deletion strain
por: Xu, Mengwei, et al.
Publicado: (2023) -
Effects of Intranasal Pseudorabies Virus AH02LA Infection on Microbial Community and Immune Status in the Ileum and Colon of Piglets
por: Zhang, Chuanjian, et al.
Publicado: (2019) -
A gD&gC-substituted pseudorabies virus vaccine strain provides complete clinical protection and is helpful to prevent virus shedding against challenge by a Chinese pseudorabies variant
por: Zhang, Chuanjian, et al.
Publicado: (2019) -
Identification of four insertion sites for foreign genes in a pseudorabies virus vector
por: Zhang, Chuanjian, et al.
Publicado: (2021)