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Overlapping group screening for detection of gene-gene interactions: application to gene expression profiles with survival trait

BACKGROUND: The development of a disease is a complex process that may result from joint effects of multiple genes. In this article, we propose the overlapping group screening (OGS) approach to determining active genes and gene-gene interactions incorporating prior pathway information. The OGS metho...

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Detalles Bibliográficos
Autores principales: Wang, Jie-Huei, Chen, Yi-Hau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150983/
https://www.ncbi.nlm.nih.gov/pubmed/30241463
http://dx.doi.org/10.1186/s12859-018-2372-2