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Overlapping group screening for detection of gene-gene interactions: application to gene expression profiles with survival trait
BACKGROUND: The development of a disease is a complex process that may result from joint effects of multiple genes. In this article, we propose the overlapping group screening (OGS) approach to determining active genes and gene-gene interactions incorporating prior pathway information. The OGS metho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150983/ https://www.ncbi.nlm.nih.gov/pubmed/30241463 http://dx.doi.org/10.1186/s12859-018-2372-2 |