CD38 is methylated in prostate cancer and regulates extracellular NAD(+)

BACKGROUND: Cancer cell metabolism requires sustained pools of intracellular nicotinamide adenine dinucleotide (NAD(+)) which is maintained by a balance of NAD(+) hydrolase activity and NAD(+) salvage activity. We recently reported that human prostate cancer can be initiated following oncogene expre...

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Detalles Bibliográficos
Autores principales: Mottahedeh, Jack, Haffner, Michael C., Grogan, Tristan R., Hashimoto, Takao, Crowell, Preston D., Beltran, Himisha, Sboner, Andrea, Bareja, Rohan, Esopi, David, Isaacs, William B., Yegnasubramanian, Srinivasan, Rettig, Matthew B., Elashoff, David A., Platz, Elizabeth A., De Marzo, Angelo M., Teitell, Michael A., Goldstein, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150989/
https://www.ncbi.nlm.nih.gov/pubmed/30258629
http://dx.doi.org/10.1186/s40170-018-0186-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150989/
https://www.ncbi.nlm.nih.gov/pubmed/30258629
http://dx.doi.org/10.1186/s40170-018-0186-3

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