Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice

BACKGROUND: Undoubtedly, neuroinflammation is a major contributor to Alzheimer’s disease (AD) progression. Neuroinflammation is characterized by the activity of brain resident glial cells, in particular microglia, but also by peripheral immune cells, which infiltrate the brain at certain stages of d...

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Detalles Bibliográficos
Autores principales: Unger, M. S., Schernthaner, P., Marschallinger, J., Mrowetz, H., Aigner, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151006/
https://www.ncbi.nlm.nih.gov/pubmed/30241479
http://dx.doi.org/10.1186/s12974-018-1304-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151006/
https://www.ncbi.nlm.nih.gov/pubmed/30241479
http://dx.doi.org/10.1186/s12974-018-1304-4

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