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Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice

Fragile X syndrome is caused by the loss of fragile X mental retardation protein (FMRP). Kainate receptor (KAR) is a subfamily of ionotropic glutamate receptors (iGluR) that acts mainly as a neuromodulator of synaptic transmission and neuronal excitability. However, little is known about the changes...

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Detalles Bibliográficos
Autores principales: Qiu, Shuang, Wu, Yu, Lv, Xinyou, Li, Xia, Zhuo, Min, Koga, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151036/
https://www.ncbi.nlm.nih.gov/pubmed/30241548
http://dx.doi.org/10.1186/s13041-018-0396-1