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Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice
Fragile X syndrome is caused by the loss of fragile X mental retardation protein (FMRP). Kainate receptor (KAR) is a subfamily of ionotropic glutamate receptors (iGluR) that acts mainly as a neuromodulator of synaptic transmission and neuronal excitability. However, little is known about the changes...
Autores principales: | Qiu, Shuang, Wu, Yu, Lv, Xinyou, Li, Xia, Zhuo, Min, Koga, Kohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151036/ https://www.ncbi.nlm.nih.gov/pubmed/30241548 http://dx.doi.org/10.1186/s13041-018-0396-1 |
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