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Treatment with olaparib monotherapy for BRCA2-mutated refractory intrahepatic cholangiocarcinoma: a case report

Olaparib is an oral poly ADP-ribose polymerase inhibitor with activity in germline BRCA1 and BRCA2 (BRCA1/2)-associated breast and ovarian cancers. There is no report about treatment with olaparib in BRCA1/2-mutated intrahepatic cholangiocarcinomas. This study is to observe the efficacy and safety o...

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Detalles Bibliográficos
Autores principales: Cheng, Yuan, Zhang, Juan, Qin, Shu kui, Hua, Hai qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151096/
https://www.ncbi.nlm.nih.gov/pubmed/30271179
http://dx.doi.org/10.2147/OTT.S176914