Phase 2b placebo-controlled trial of M72/AS01(E) candidate vaccine to prevent active tuberculosis in adults

BACKGROUND: A tuberculosis vaccine to interrupt transmission is urgently needed. We assessed the safety and efficacy of the candidate tuberculosis vaccine, M72/AS01(E), against progression to bacteriologically-confirmed active pulmonary tuberculosis disease in adults with latent Mycobacterium tuberc...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Der Meeren, Olivier, Hatherill, Mark, Nduba, Videlis, Wilkinson, Robert J, Muyoyeta, Monde, Van Brakel, Elana, Ayles, Helen M, Henostroza, German, Thienemann, Friedrich, Scriba, Thomas J., Diacon, Andreas, Blatner, Gretta L., Demoitié, Marie-Ange, Tameris, Michele, Malahleha, Mookho, Innes, James C., Hellstrom, Elizabeth, Martinson, Neil, Singh, Tina, Akite, Elaine Jacqueline, Khatoon, Aisha, Bollaerts, Anne, Ginsberg, Ann M., Evans, Thomas G., Gillard, Paul, Tait, Dereck R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151253/
https://www.ncbi.nlm.nih.gov/pubmed/30280651
http://dx.doi.org/10.1056/NEJMoa1803484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151253/
https://www.ncbi.nlm.nih.gov/pubmed/30280651
http://dx.doi.org/10.1056/NEJMoa1803484

Ejemplares similares