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The progression of severe aplastic anemia to hypoplastic leukemia in a long-term observation after the administration of pegylated rHuMGDF

Thrombopoietin (TPO) is a critical regulator of hematopoiesis. We previously reported that a severe aplastic anemia (SAA) who received a short-term administration of pegylated recombinant human megakaryocyte growth and development factor (rHuMGDF). A trilineage hematologic response was induced, howe...

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Detalles Bibliográficos
Autores principales: Ishikawa, Maho, Matsuda, Akira, Okamura, Daisuke, Maeda, Tomoya, Kawai, Nobutaka, Asou, Norio, Bessho, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151347/
https://www.ncbi.nlm.nih.gov/pubmed/30283622
http://dx.doi.org/10.4081/hr.2018.7679