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Detecting GPC3-Expressing Hepatocellular Carcinoma with L5 Peptide-Guided Pretargeting Approach: In Vitro and In Vivo MR Imaging Experiments

OBJECTIVE: To investigate the potential of L5 peptide-guided pretargeting approach to identify GPC3-expressing hepatocellular carcinoma (HCC) using ultrasmall superparamagnetic iron oxide (USPIO) as the MR probe. METHODS: Immunofluorescence with carboxyfluorescein- (FAM-) labeled L5 peptide was perf...

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Detalles Bibliográficos
Autores principales: Li, Weiyue, Xiao, Xiang, Li, Xiaodan, Xu, Yikai, Ma, Lichao, Guo, Liuji, Yan, Chenggong, Wu, Yuankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151370/
https://www.ncbi.nlm.nih.gov/pubmed/30275801
http://dx.doi.org/10.1155/2018/9169072