Sulfadiazine Salicylaldehyde-Based Schiff Bases: Synthesis, Antimicrobial Activity and Cytotoxicity

The resistance among microbes has brought an urgent need for new drugs. Thus, we synthesized a series of Schiff bases derived from the sulfa drug sulfadiazine and various salicylaldehydes. The resulting 4-[(2-hydroxybenzylidene)amino]-N-(pyrimidin-2-yl)benzene-sulfonamides were characterized and eva...

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Detalles Bibliográficos
Autores principales: Krátký, Martin, Dzurková, Magdaléna, Janoušek, Jiří, Konečná, Klára, Trejtnar, František, Stolaříková, Jiřina, Vinšová, Jarmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151383/
https://www.ncbi.nlm.nih.gov/pubmed/28925956
http://dx.doi.org/10.3390/molecules22091573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151383/
https://www.ncbi.nlm.nih.gov/pubmed/28925956
http://dx.doi.org/10.3390/molecules22091573

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