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Andrographolide Suppresses MV4-11 Cell Proliferation through the Inhibition of FLT3 Signaling, Fatty Acid Synthesis and Cellular Iron Uptake

Background: Andrographolide (ADR), the main active component of Andrographis paniculata, displays anticancer activity in various cancer cell lines, among which leukemia cell lines exhibit the highest sensitivity to ADR. In particular, ADR was also reported to have reduced drug resistance in multidru...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Zhang, Jianbin, Yuan, Lixia, Lay, Yifei, Wong, Yin Kwan, Lim, Teck Kwang, Ong, Chye Sun, Lin, Qingsong, Wang, Jigang, Hua, Zichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151431/
https://www.ncbi.nlm.nih.gov/pubmed/28858244
http://dx.doi.org/10.3390/molecules22091444