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Efficacy of Bioactive Cyclic Peptides in Rheumatoid Arthritis: Translation from In Vitro to In Vivo Models

Using a novel drug discovery technology reported in previous issues of this journal cyclic peptides have been created which are able to down-regulate secretion of inflammatory cytokines, in vitro, by stimulated cells of the macrophage cell line J774. The cytokines in question, TNF-alpha and IL-6, ar...

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Detalles Bibliográficos
Autores principales: New, Roger, Bogus, Michal, Bansal, Gurpal S., Dryjska, Malgorzata, Zajkowska, Katarzyna, Burnet, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151468/
https://www.ncbi.nlm.nih.gov/pubmed/28946707
http://dx.doi.org/10.3390/molecules22101613