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Design, Synthesis, and Antitumor Activity of Novel Quinazoline Derivatives

In an attempt to explore a new class of epidermal growth factor receptor (EGFR) inhibitors, novel 4-stilbenylamino quinazoline derivatives were synthesized through a Dimorth rearrangement reaction and characterized via IR, (1)H-NMR, (13)C-NMR, and HRMS. Methoxyl, methyl, halogen, and trifluoromethyl...

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Detalles Bibliográficos
Autores principales: Wang, Liuchang, Li, Pengna, Li, Baolin, Wang, Yawen, Li, Jiangtao, Song, Limei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151509/
https://www.ncbi.nlm.nih.gov/pubmed/28956845
http://dx.doi.org/10.3390/molecules22101624