Rational Design of Nucleoside–Bile Acid Conjugates Incorporating a Triazole Moiety for Anticancer Evaluation and SAR Exploration

Herein we report a study on the synthesis and biological evaluation of a library of nucleoside-bile acid conjugates prepared by combining 2′-deoxyadenosine, 2′-deoxyguanosine, 2′-deoxyuridine as well as adenosine and guanosine derivatives with cheno-, urso-, nor-cheno-, nor-urso- and taurourso-desox...

Descripción completa

Detalles Bibliográficos
Autores principales: Navacchia, Maria Luisa, Marchesi, Elena, Mari, Lara, Chinaglia, Nicola, Gallerani, Eleonora, Gavioli, Riccardo, Capobianco, Massimo Luigi, Perrone, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151511/
https://www.ncbi.nlm.nih.gov/pubmed/29023408
http://dx.doi.org/10.3390/molecules22101710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151511/
https://www.ncbi.nlm.nih.gov/pubmed/29023408
http://dx.doi.org/10.3390/molecules22101710

Ejemplares similares