Studying the Structural Significance of Galectin Design by Playing a Modular Puzzle: Homodimer Generation from Human Tandem-Repeat-Type (Heterodimeric) Galectin-8 by Domain Shuffling

Tissue lectins are emerging (patho)physiological effectors with broad significance. The capacity of adhesion/growth-regulatory galectins to form functional complexes with distinct cellular glycoconjugates is based on molecular selection of matching partners. Engineering of variants by changing the t...

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Detalles Bibliográficos
Autores principales: Ludwig, Anna-Kristin, Michalak, Malwina, Shilova, Nadya, André, Sabine, Kaltner, Herbert, Bovin, Nicolai V., Kopitz, Jürgen, Gabius, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151538/
https://www.ncbi.nlm.nih.gov/pubmed/28925965
http://dx.doi.org/10.3390/molecules22091572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151538/
https://www.ncbi.nlm.nih.gov/pubmed/28925965
http://dx.doi.org/10.3390/molecules22091572

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