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Forbidden Coherence Transfer of (19)F Nuclei to Quantitatively Measure the Dynamics of a CF(3)-Containing Ligand in Receptor-Bound States

The dynamic property of a ligand in the receptor-bound state is an important metric to characterize the interactions in the ligand–receptor interface, and the development of an experimental strategy to quantify the amplitude of motions in the bound state is of importance to introduce the dynamic asp...

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Detalles Bibliográficos
Autores principales: Tokunaga, Yuji, Takeuchi, Koh, Shimada, Ichio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151541/
https://www.ncbi.nlm.nih.gov/pubmed/28880244
http://dx.doi.org/10.3390/molecules22091492