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Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway

AKT, a serine/threonine protein kinase and mammalian target of rapamycin (mTOR) plays a critical role in the proliferation and resistance to apoptosis that are essential to the development and progression of colon cancer. Therefore, AKT/mTOR signaling pathway has been recognized as an attractive tar...

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Detalles Bibliográficos
Autores principales: Kapral, Małgorzata, Wawszczyk, Joanna, Jesse, Katarzyna, Paul-Samojedny, Monika, Kuśmierz, Dariusz, Węglarz, Ludmiła
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151581/
https://www.ncbi.nlm.nih.gov/pubmed/28972559
http://dx.doi.org/10.3390/molecules22101657