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Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway
AKT, a serine/threonine protein kinase and mammalian target of rapamycin (mTOR) plays a critical role in the proliferation and resistance to apoptosis that are essential to the development and progression of colon cancer. Therefore, AKT/mTOR signaling pathway has been recognized as an attractive tar...
Autores principales: | Kapral, Małgorzata, Wawszczyk, Joanna, Jesse, Katarzyna, Paul-Samojedny, Monika, Kuśmierz, Dariusz, Węglarz, Ludmiła |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151581/ https://www.ncbi.nlm.nih.gov/pubmed/28972559 http://dx.doi.org/10.3390/molecules22101657 |
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