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High linear energy transfer carbon-ion irradiation increases the release of the immune mediator high mobility group box 1 from human cancer cells

Anti-tumor immunity modulates the local effects of radiation therapy. High mobility group box 1 (HMGB1) plays a pivotal role in activating antigen-specific T-cell responses. Here, we examined the relationship between linear energy transfer (LET) and HMGB1 release. We assessed the proportions of KYSE...

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Detalles Bibliográficos
Autores principales: Onishi, Masahiro, Okonogi, Noriyuki, Oike, Takahiro, Yoshimoto, Yuya, Sato, Hiro, Suzuki, Yoshiyuki, Kamada, Tadashi, Nakano, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151640/
https://www.ncbi.nlm.nih.gov/pubmed/29947767
http://dx.doi.org/10.1093/jrr/rry049