Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents

A medium-throughput screen using Mycobacterium tuberculosis H37Rv was employed to screen an in-house library of structurally diverse compounds for antimycobacterial activity. In this initial screen, eleven 7-substituted coumarin derivatives with confirmed monoamine oxidase-B and cholinesterase inhib...

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Detalles Bibliográficos
Autores principales: Kapp, Erika, Visser, Hanri, Sampson, Samantha L., Malan, Sarel F., Streicher, Elizabeth M., Foka, Germaine B., Warner, Digby F., Omoruyi, Sylvester I., Enogieru, Adaze B., Ekpo, Okobi E., Zindo, Frank T., Joubert, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151660/
https://www.ncbi.nlm.nih.gov/pubmed/28973990
http://dx.doi.org/10.3390/molecules22101644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151660/
https://www.ncbi.nlm.nih.gov/pubmed/28973990
http://dx.doi.org/10.3390/molecules22101644

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