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Effect of Sipjeondaebo-Tang on the Pharmacokinetics of S-1, an Anticancer Agent, in Rats Evaluated by Population Pharmacokinetic Modeling

S-1 (TS-1(®)) is an oral fluoropyrimidine anticancer agent containing tegafur, oteracil, and gimeracil. Sipjeondaebo-tang (SDT) is a traditional oriental herbal medicine that has potential to alleviate chemotherapy-related adverse effects. The aim of the present study was to evaluate the effect of S...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hwan, Shin, Soyoung, Shin, Jeong Cheol, Bulitta, Jürgen B., Weon, Kwon-Yeon, Yoo, Sun Dong, Park, Gi-Young, Jeong, Seok Won, Kwon, Dong Rak, Min, Byung Sun, Woo, Mi Hee, Shin, Beom Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151713/
https://www.ncbi.nlm.nih.gov/pubmed/28880240
http://dx.doi.org/10.3390/molecules22091488