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Transesterification Synthesis of Chloramphenicol Esters with the Lipase from Bacillus amyloliquefaciens

This work presents a synthetic route to produce chloramphenicol esters by taking advantage the high enantio- and regio-selectivity of lipases. A series of chloramphenicol esters were synthesized using chloramphenicol, acyl donors of different carbon chain length and lipase Lip(BA) (lipase cloned fro...

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Detalles Bibliográficos
Autores principales: Dong, Fengying, Li, Lingmeng, Lin, Lin, He, Dannong, Chen, Jingwen, Wei, Wei, Wei, Dongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151736/
https://www.ncbi.nlm.nih.gov/pubmed/28925953
http://dx.doi.org/10.3390/molecules22091523