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Long Term Osmotic Mini Pump Treatment with Alpha-MSH Improves Myocardial Function in Zucker Diabetic Fatty Rats

The present investigation evaluates the cardiovascular effects of the anorexigenic mediator alpha-melanocyte stimulating hormone (MSH), in a rat model of type 2 diabetes. Osmotic mini pumps delivering MSH or vehicle, for 6 weeks, were surgically implanted in Zucker Diabetic Fatty (ZDF) rats. Serum p...

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Detalles Bibliográficos
Autores principales: Szokol, Miklos, Priksz, Daniel, Bombicz, Mariann, Varga, Balazs, Kovacs, Arpad, Fulop, Gabor Aron, Csipo, Tamas, Posa, Aniko, Toth, Attila, Papp, Zoltan, Szilvassy, Zoltan, Juhasz, Bela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151765/
https://www.ncbi.nlm.nih.gov/pubmed/29023410
http://dx.doi.org/10.3390/molecules22101702