Applications of PNA-Based Artificial Restriction DNA Cutters

More than ten years ago, artificial restriction DNA cutters were developed by combining two pseudo-complementary peptide nucleic acid (pcPNA) strands with either Ce(IV)/EDTA or S1 nuclease. They have remarkably high site-specificity and can cut only one predetermined site in the human genome. In thi...

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Detalles Bibliográficos
Autores principales: Shigi, Narumi, Sumaoka, Jun, Komiyama, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151779/
https://www.ncbi.nlm.nih.gov/pubmed/28934140
http://dx.doi.org/10.3390/molecules22101586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151779/
https://www.ncbi.nlm.nih.gov/pubmed/28934140
http://dx.doi.org/10.3390/molecules22101586

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