Development and Validation of HPLC-DAD and UHPLC-DAD Methods for the Simultaneous Determination of Guanylhydrazone Derivatives Employing a Factorial Design

Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an excellent tool in the optimization of a chromatographic method, because it is possible quickly change factors such as temperature, mobile phase com...

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Detalles Bibliográficos
Autores principales: Azevedo de Brito, Wanessa, Gomes Dantas, Monique, Andrade Nogueira, Fernando Henrique, Ferreira da Silva-Júnior, Edeildo, Xavier de Araújo-Júnior, João, de Aquino, Thiago Mendonça, Adélia Nogueira Ribeiro, Êurica, da Silva Solon, Lilian Grace, Soares Aragão, Cícero Flávio, Barreto Gomes, Ana Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151785/
https://www.ncbi.nlm.nih.gov/pubmed/28867762
http://dx.doi.org/10.3390/molecules22091394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151785/
https://www.ncbi.nlm.nih.gov/pubmed/28867762
http://dx.doi.org/10.3390/molecules22091394

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