High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents (‡)

Boron cluster-modified therapeutic nucleic acids with improved properties are of interest in gene therapy and in cancer boron neutron capture therapy (BNCT). High metallacarborane-loaded antisense oligonucleotides (ASOs) targeting epidermal growth factor receptor (EGFR) were synthesized through post...

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Detalles Bibliográficos
Autores principales: Kaniowski, Damian, Ebenryter-Olbińska, Katarzyna, Sobczak, Milena, Wojtczak, Błażej, Janczak, Sławomir, Leśnikowski, Zbigniew J., Nawrot, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151803/
https://www.ncbi.nlm.nih.gov/pubmed/28832537
http://dx.doi.org/10.3390/molecules22091393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151803/
https://www.ncbi.nlm.nih.gov/pubmed/28832537
http://dx.doi.org/10.3390/molecules22091393

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