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β-Amyloid and the Pathomechanisms of Alzheimer’s Disease: A Comprehensive View

Protein dyshomeostasis is the common mechanism of neurodegenerative diseases such as Alzheimer’s disease (AD). Aging is the key risk factor, as the capacity of the proteostasis network declines during aging. Different cellular stress conditions result in the up-regulation of the neurotrophic, neurop...

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Detalles Bibliográficos
Autores principales: Penke, Botond, Bogár, Ferenc, Fülöp, Lívia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151811/
https://www.ncbi.nlm.nih.gov/pubmed/28994715
http://dx.doi.org/10.3390/molecules22101692