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CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma

BACKGROUND: Glioblastoma (GBM) was shown to relapse faster and displayed therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor cell-driven mechanism of neovascularization called vascular mimicry (VM). We identified highly upregulated interleukin 8 (IL-8)-CXCR2 axis i...

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Detalles Bibliográficos
Autores principales: Angara, Kartik, Borin, Thaiz F., Rashid, Mohammad H., Lebedyeva, Iryna, Ara, Roxan, Lin, Ping-Chang, Iskander, ASM, Bollag, Roni J., Achyut, Bhagelu R., Arbab, Ali S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151844/
https://www.ncbi.nlm.nih.gov/pubmed/30236892
http://dx.doi.org/10.1016/j.neo.2018.08.011