Cargando…
CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma
BACKGROUND: Glioblastoma (GBM) was shown to relapse faster and displayed therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor cell-driven mechanism of neovascularization called vascular mimicry (VM). We identified highly upregulated interleukin 8 (IL-8)-CXCR2 axis i...
Autores principales: | Angara, Kartik, Borin, Thaiz F., Rashid, Mohammad H., Lebedyeva, Iryna, Ara, Roxan, Lin, Ping-Chang, Iskander, ASM, Bollag, Roni J., Achyut, Bhagelu R., Arbab, Ali S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151844/ https://www.ncbi.nlm.nih.gov/pubmed/30236892 http://dx.doi.org/10.1016/j.neo.2018.08.011 |
Ejemplares similares
-
Changes in the tumor microenvironment and outcome for TME-targeting therapy in glioblastoma: A pilot study
por: Ali, Sehar, et al.
Publicado: (2021) -
HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model
por: Borin, Thaiz F., et al.
Publicado: (2017) -
Vascular Mimicry: A Novel Neovascularization Mechanism Driving Anti-Angiogenic Therapy (AAT) Resistance in Glioblastoma
por: Angara, Kartik, et al.
Publicado: (2017) -
Intravenous Formulation of HET0016 Decreased Human Glioblastoma Growth and Implicated Survival Benefit in Rat Xenograft Models
por: Jain, Meenu, et al.
Publicado: (2017) -
Major Challenges and Potential Microenvironment-Targeted Therapies in Glioblastoma
por: Arbab, Ali S., et al.
Publicado: (2017)