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CRISPR/Cas9-mediated hypoxia inducible factor-1α knockout enhances the antitumor effect of transarterial embolization in hepatocellular carcinoma

Transarterial embolization (TAE) is a palliative option commonly used for the treatment of advanced, unresectable hepatocellular carcinoma (HCC). However, patient prognosis in regards to overall survival has not improved with this method, mainly due to hypoxia-inducible factor-1α (HIF-1α)-induced an...

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Detalles Bibliográficos
Autores principales: Liu, Quan, Fan, Dahua, Adah, Dickson, Wu, Zhengzhi, Liu, Renyan, Yan, Qiao-Ting, Zhang, Yue, Du, Zhi-Yong, Wang, Dou, Li, Yan, Bao, Shi-Yun, Liu, Li-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151876/
https://www.ncbi.nlm.nih.gov/pubmed/30226584
http://dx.doi.org/10.3892/or.2018.6667