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STAT1-HDAC4 signaling induces epithelial-mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2

Our previous studies have shown that the novel oncogene, cancer upregulated gene 2 (CUG2), activates STAT1, which is linked to anticancer drug resistance, induces epithelial-mesenchymal transition (EMT) and cancer stem cell-like phenotypes as determined by MTT, migration and sphere formation assays....

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Detalles Bibliográficos
Autores principales: Kaowinn, Sirichat, Kaewpiboon, Chutima, Koh, Sang Seok, Krämer, Oliver H., Chung, Young-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151883/
https://www.ncbi.nlm.nih.gov/pubmed/30226605
http://dx.doi.org/10.3892/or.2018.6701