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CIP2A depletion potentiates the chemosensitivity of cisplatin by inducing increased apoptosis in bladder cancer cells

Poor response and chemotherapy resistance to cisplatin (DDP)-based therapy frequently lead to treatment failure in advanced bladder cancer; however the underlying mechanism is extremely complex and unclear. Furthermore, cancerous inhibitor of protein phosphatase 2A (CIP2A), a recently identified hum...

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Detalles Bibliográficos
Autores principales: Gao, Fengbin, Wang, Xiaojing, Chen, Shanwen, Xu, Tianyuan, Wang, Xianjin, Shen, Yifan, Dong, Fan, Zhong, Shan, Shen, Zhoujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151887/
https://www.ncbi.nlm.nih.gov/pubmed/30106121
http://dx.doi.org/10.3892/or.2018.6641