Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors

The development of isoform selective inhibitors of the carbonic anhydrase (CA; EC 4.2.1.1) enzymes represents the key approach for the successful development of druggable small molecules. Herein we report a series of new benzenesulfamide derivatives (-NH-SO(2)NH(2)) bearing the 1-benzhydrylpiperazin...

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Detalles Bibliográficos
Autores principales: Berrino, Emanuela, Bua, Silvia, Mori, Mattia, Botta, Maurizio, Murthy, Vallabhaneni S., Vijayakumar, Vijayaparthasarathi, Tamboli, Yasinalli, Bartolucci, Gianluca, Mugelli, Alessandro, Cerbai, Elisabetta, Supuran, Claudiu T., Carta, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151984/
https://www.ncbi.nlm.nih.gov/pubmed/28672822
http://dx.doi.org/10.3390/molecules22071049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151984/
https://www.ncbi.nlm.nih.gov/pubmed/28672822
http://dx.doi.org/10.3390/molecules22071049

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